Vanquish™ Systems

Designed with innovative technology and fine detail, the Thermo Scientific™ Vanquish™ UHPLC System delivers a new standard in high-end UHPLC—more results with better separations and easier interaction simultaneously, without compromise. Conceived for the uniquely efficient 1.5µm solid core particle Thermo Scientific™ Accucore™ Vanquish™ C18 UHPLC column, this fully integrated and biocompatible system features high sample capacity for high-throughput workflows, industry-leading pumping performance, amazingly high S/N and linearity, two-mode thermostatting, active preheating, and more in a system that's driven by the gold-standard CDS software

Vanquish™ UHPLC System – High Performance UHPLC

  • Record data over the entire weekend. Out of the box, Vanquish system's Split Sampler HT module comes with a vial capacity of 208 samples. Increase to 8832 sample capacity (23 well plates) by adding the optional Thermo Scientific™ Vanquish™ Charger
  • Higher pump pressure: 1500 bar (22,000 psi) pump pressure
  • Higher flow rate: up to 5mL/min
  • Up to nine different solvent combinations without stopping your experiment to replace solvents
  • Temperature range from 5°C to 120°C

  • Vanquish™ Flex UHPLC System – Built for Biopharma

  • Out of the box, Vanquish Flex Split Sampler FT module comes with a vial capacity of 216 samples. Increase to 8832 sample capacity (23 well plates) by adding the optional Vanquish Charger module
  • 1000bar (15,000psi) of pump pressure and flow rates up to 8mL/min
  • Binary and querternary option
  • Temperature range from 5°C – 120°C
  • Active pre-heating and post column cooling

  • For research use only.  Not for use in diagnostic procedures.


    Ultimate™ 3000 Systems

    Perform the full range of rapid HPLC and UHPLC applications on one system. Thermo Scientific™ UltiMate™ 3000 Rapid Separation systems combine unique hardware features and the ability to use small particle columns for fast separations with excellent resolution. All system components are coordinated for high performance. Available in biocompatible and non-biocompatible setups and featuring unique technological innovations like dual-gradient capabilities, the UltiMate 3000 RS systems sustain even most advanced workflows

    UltiMate™ 3000 RS systems

  • Up to 8mL/min flow rate supporting up to 100 MPa (15000 psi/1000 bar) backpressure for column format and column particle size flexibility
  • Binary and querternary option
  • Get support for high temperature chromatography up to 110°C (383 K) to reduce system backpressure from the mobile phase heater and post-column cooler included
  • Obtain near-zero dead volume connections for optimal peak shapes even over extended periods using Thermo Scientific™ Dionex™ Viper™ Fingertight Fitting system
  • Minimize contamination between samples for more accurate results using ultra-low carryover autosamplers (with loop and needle permanently in the flow path)

  • UltiMate™ 3000 SD systems

  • Up to 10 mL/min flow rate supporting up to 62 MPa (9000 psi/620 bar) backpressure for column format and column particle size flexibility
  • Binary and querternary option
  • Get near-zero dead volume connections for optimal peak shapes even over extended periods by using Thermo Scientific™ Dionex™ Viper™ Fingertight fitting system
  • Minimize contamination between samples for more accurate results using ultra-low carryover autosamplers (with loop and needle permanently in the flow path)
  • Optimize mixing efficiency with adjustable gradient delay volumes using Thermo Scientific™ Dionex™ SpinFlow™ technology

  • UltiMate™ 3000 Dual systems

  • RS and SD option
  • Two independently operating ternary gradient pumps for exceptional column format and particle size flexibility
  • On-line SPE capability
  • Get near-zero dead volume connections for optimal peak shapes even over extended periods by using Thermo Scientific™ Dionex™ Viper™ Fingertight fitting system
  • Minimize contamination between samples for more accurate results using ultra-low carryover autosamplers (with loop and needle permanently in the flow path)
  • Optimize mixing efficiency with adjustable gradient delay volumes using Thermo Scientific™ Dionex™ SpinFlow™ technology

  • UltiMate™ 3000 RSLCNano system

  • ProFlow technology for nano flow applications provides the highest level of retention time precision
  • Capillary flow meter enables high-sensitivity with high-throughput analyses for reliable routine assays
  • Continuous-flow high pressure gradient pump provides uninterrupted gradient delivery permitting ultra-long gradients
  • An additional micro flow pump provides uninterrupted continuous flow through the trap and analytical column, even during sample loading, making sample pre-concentration and two dimensional workflows possible
  • UHPLC pressure capability of up to 860 bar for high performance separations
  • Wide flow rate range from 50nL/min to 50µL/min

  • For research use only.  Not for use in diagnostic procedures.


    EASY-nLC™ 1200 System

    Get simplicity and high-throughput capacity in a nano-flow UHPLC. The new Thermo Scientific™ EASY-nLC™ 1200 system is optimized, fully integrated and designed for users at any level of expertise. A pressure rating of 1200 bar provides reduced cycle times and increased throughput. New maintenance-free ceramic valves, tool-free connections (Thermo Scientific™ nanoViper™ Fingertight Fittings) and new software features gives you intelligent system maintenance, results in less system downtime, lower cost of ownership, reliable and fast connections for a robust, and an easily serviceable system ultimately leading to better MS data

    Increased System Robustness and Serviceability

  • New maintenance-free ceramic valves result in extraordinary dependability and lower cost of ownership
  • nanoViper connections for tool-free, reliable and fast connections
  • Enables use of longer analytical columns for higher peak capacity
  • Automated, built-in maintenance routine
  • User friendly leak tests pinpoint position of leaks
  • Robust performance and increased throughput during loading and equilibration steps from Thermo Scientific™ Intelligent Flow Control (IFC™)
  • Advanced pressure test quickly diagnoses blocked capillaries
  • Remote access capability for system interrogation and technical support
  • Outstanding reproducibility throughout your injection sequence during gradient delivery from Thermo Scientific™ Automatic Flow Control (AFC™)

  • For research use only.  Not for use in diagnostic procedures.


    Transcend™II System with Multi-channel and TurboFlow™Technology

    Improve data quality, lower costs, and increase LC/MS throughput without compromising data quality or sensitivity. The Thermo Scientific™ Transcend™ II system combines proprietary Thermo Scientific™ TurboFlow™ online sample preparation technology and a unique HPLC multi-channel technique to bring the productivity of up to four separate, parallel UHPLC channels to a single mass spectrometer. It reduces sample preparation time up to 95% and maximizes utilization of MS instruments

    Technology Dramatically Reduces Sample Preparation

  • Minimizes manual sample preparation and facilitates direct sample injection into an LC-MS system—including plasma, urine, food, and other complex matrices
  • Reduces ion suppression through higher specificity
  • Saves time and simplifies complex sample preparation protocols
  • Simplifies method development by enabling the same method to be used for different matrices
  • Multiplexing brings the productivity of up to four separate, parallel UHPLC channels to a single mass spectrometer. With the Thermo Scientific™ Aria™ operating software, each channel operates independently, so a single method or multiple methods can be run simultaneously
  • Aria software controls pump operation, valve switching, cleaning, and gradient procedures on the Transcend system. Compatible with all leading mass spectrometer software, the intuitive graphical user interface makes it simple to run a TurboFlow method or set up multiplexing
  • Enhances productivity by facilitating analysis of more samples per hour
  • Increases flexibility by allowing up to four different assays to run at the same time

  • For research use only.  Not for use in diagnostic procedures.