Prelude MD™ HPLC

Help meet the demand for fast, accurate in vitro diagnostic tests with the Thermo Scientific™ Prelude MD™ HPLC. The Prelude MD HPLC, a Class I medical device, provides automated sample cleanup and two channels of HPLC separation for greater productivity and certainty from laboratory-developed clinical diagnostic tests. Combine the Prelude MD HPLC with the Thermo Scientific™ Endura MD™ mass spectrometer and ClinQuan MD™ software, and get the quantitative accuracy of LC-MS easily and confidently
U.S. FDA listed Class I medical device. CE IVDD compliant

Confidence in results with ease and efficiency

  • Thermo Scientific™ TurboFlow™ technology can automate many sample cleanup tasks, greatly reducing error-prone manual steps that result in variability
  • TurboFlow technology removes matrix interferences and captures analytes of interest, minimizing ion suppression and improving subsequent mass spectrometry results
  • Integrated syringe pumps deliver accurate, reproducible mobile phase flow and gradients
  • Dual HPLC channels are intelligently optimized to run identical or different tests in parallel, maximizing utilization of the mass spectrometer and improving turnaround time and productivity


  • Endura MD™ Mass Spectrometer

    Develop in vitro diagnostic tests that leverage the sensitivity, quantitative accuracy, and confidence of mass spectrometry with the Thermo Scientific™ Endura MD™ mass spectrometer. The Endura MD instrument, a Class I medical device, combines excellent sensitivity, quantitative performance, and robustness with built-in usability to help deliver more value and worry-free results from laboratory-developed clinical diagnostic tests. Combine the Endura MD MS with the Thermo Scientific™ Prelude MD™ HPLC and ClinQuan MD™ software, and get the quantitative accuracy of LC-MS easily and confidently
    U.S. FDA listed Class I medical device. CE IVDD compliant

    Confidence in results

  • Delivers excellent sensitivity for a wide range of compounds and matrices
  • Minimizes signal noise by removing more solvent vapor and blocking neutrals
  • Provides five orders of dynamic range for accurate quantitation of even low-concentration or limited samples
  • Features ultrafast selected-reaction monitoring (SRM) so more transitions can be monitored for greater confidence
  • Accommodates both HESI and APCI probes, which can be operated in either positive or negative ion modes to meet varied analytical demands

  • Outstanding robustness

  • Reduces the amount of solvent vapor introduced into the vacuum system for greater robustness and reduced maintenance
  • Blocks neutrals, keeping the ion optics cleaner and performing better
  • Maintains mass accuracy and stability with advanced electronics
  • Uses CLIA-compliant ClinQuan MD software with simple, step-by-step processes for method selection, building sample lists, running samples, performing daily maintenance, quality control, and reporting


  • ClinQuan MD™ Software

    Confidently store, retrieve and process data from laboratory-developed in vitro diagnostic tests using CLIA-compliant Thermo Scientific™ ClinQuan MD™ software. ClinQuan MD software, a Class I medical device, quickly and confidently processes patient test data and reports the results. Combine ClinQuan MD software with the Thermo Scientific™ Endura MD™ mass spectrometer and Prelude MD™ HPLC to achieve the quantitative accuracy of LC-MS easily and confidently
    U.S. FDA listed Class I medical device. CE IVDD compliant

    Store, retrieve, and process data with confidence

  • Software addresses Clinical Laboratory Improvements Amendments (CLIA) requirements with three default permission levels: lab director, supervisor (technical consultant), and technician (testing personnel)
  • Simplified user interface makes routine quantitation simple, fast, and productive with step-by-step processes for method selection, building sample lists, running samples, performing daily maintenance, quality control, and reporting
  • Time-stamped audit trails help ensure the integrity of results; all user actions are recorded, from method building to reviewing and reporting data